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ANTP Class
Families List  Genes List
En Family
The En or engrailed gene family includes two human genes, one amphioxus gene (AmphiEn) and two tandemly arranged Drosophila genes (en and inv). The relatively close linkage of mammalian Gbx genes to MNX1 and EN2 originally suggested they may be part of a gene cluster (EHGbox; Pollard and Holland 2000); however subsequent genome sequencing revealed the genes are not immediate neighbours and hence it is more accurate to consider Gbx, Mnx and En genes as derivatives of extensive tandem gene duplication events that gave rise to much of the ANTP class diversity early in animal evolution (Castro and Holland 2003).

Reference(s):
Castro LFC, Holland PWH (2003) Evol Dev 5:459-465. Pollard SL, Holland PWH (2000) Curr Biol 10:1059-1062.
 
Families List of Class ANTP :
HOXL subclass
Cdx(22)Evx(17)Gbx(15)Gsx(13)Hox1(21)Hox2(13)Hox3(25)Hox4(24)Hox5(19)Hox6-8(55)
Hox9-13(15)(96)Meox(14)Mnx(15)Pdx(6)       
NKL subclass
Abox(5)Ankx(1)Barhl(16)Bari(4)Barx(10)Bsx(10)Dbx(15)Dlx(35)Emx(22)En(19)
Hhex(10)Hlx(9)Hx(1)Lbx(14)Lcx(1)Msx(22)Msxlx(3)Nanog(15)Nedx(5)Nk1(17)
Nk2.1(18)Nk2.2(15)Nk3(14)Nk4(19)Nk5/Hmx(25)Nk6(19)Nk7(4)Noto(10)Ro(5)Tlx(19)
Vax(12)Ventx(18)         
 
Loci in En of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
eng1aengrailed 1aEnZebrafish 
eng1bengrailed 1bEnZebrafish 
eng2aengrailed 2aEnZebrafish 
eng2bengrailed 2bEnZebrafish 
ceh-16C. Elegans Homeobox 16EnNematode 
En1 EnMouse 
En2 EnMouse 
EN1engrailed homeobox 1EnHuman 
EN2engrailed homeobox 2EnHuman 
EnEngrailedEnHoneybee 
InvInvectedEnHoneybee 
enengrailedEnFruitfly 
invinvectedEnFruitfly 
en1engrailed homeobox 1EnFrog 
en2engrailed homeobox 2 EnFrog 
EN1engrailed homeobox 1EnChicken 
EnEngrailedEnBeetle 
InvInvectedEnBeetle 
EnEnEnAmphioxus