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ANTP Class
Families List  Genes List
Lbx Family
The Lbx or ladybird gene family is named after the two tandemly arranged ladybird genes in Drosophila: ladybird early (lbe) and ladybird late (lbl). These form part of the NK or 93DE homeobox gene cluster (Jagla et al. 2001). In humans, there are also two Lbx genes, but these are on different chromosomes and were generated by genome duplication at the base of the vertebrates. Amphioxus has a single Lbx gene. The NK gene cluster has broken in chordates (Luke et al. 2001). Lbx genes are usually physically adjacent to Tlx genes.

Reference(s):
Jagla K, Bellard M, Frasch M (2001) BioEssays 23: 125-133. Luke GN et al. (2001) PNAS 100:5292-5295.
 
Families List of Class ANTP :
HOXL subclass
Cdx(22)Evx(17)Gbx(15)Gsx(13)Hox1(21)Hox2(13)Hox3(25)Hox4(24)Hox5(19)Hox6-8(55)
Hox9-13(15)(96)Meox(14)Mnx(15)Pdx(6)       
NKL subclass
Abox(5)Ankx(1)Barhl(16)Bari(4)Barx(10)Bsx(10)Dbx(15)Dlx(35)Emx(22)En(19)
Hhex(10)Hlx(9)Hx(1)Lbx(14)Lcx(1)Msx(22)Msxlx(3)Nanog(15)Nedx(5)Nk1(17)
Nk2.1(18)Nk2.2(15)Nk3(14)Nk4(19)Nk5/Hmx(25)Nk6(19)Nk7(4)Noto(10)Ro(5)Tlx(19)
Vax(12)Ventx(18)         
 
Loci in Lbx of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
lbx1aladybird homeobox 1aLbxZebrafish 
lbx1bladybird homeobox 1bLbxZebrafish 
lbx2ladybird homeobox homolog 2LbxZebrafish 
Lbx1 LbxMouse 
Lbx2 LbxMouse 
LBX1ladybird homeobox 1LbxHuman 
LBX2ladybird homeobox 2LbxHuman 
LbxLadybirdLbxHoneybee 
lbeladybird earlyLbxFruitfly 
lblladybird lateLbxFruitfly 
lbx1ladybird homeobox 1LbxFrog 
Lbx-lLbx likeLbxChicken 
LbxLadybirdLbxBeetle 
LbxLbxLbxAmphioxus