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ANTP Class
Families List  Genes List
Nk1 Family
The Nk1 gene family is named after Drosophila NK1, also known as slouch (slou), which is part of the NK homeobox gene cluster (Jagla et al. 2001). There are two Nk1 genes in human, on different chromosomes, generated by genome duplication at the base of the vertebrates. Amphioxus also has two Nk1 genes, but these were generated by tandem duplication (Luke et al. 2001). The NK gene cluster is broken in chordates (Luke et al. 2001).

Reference(s):
Jagla K, Bellard M, Frasch M (2001) BioEssays 23: 125-133. Luke GN et al. (2001) PNAS 100:5292-5295.
 
Families List of Class ANTP :
HOXL subclass
Cdx(22)Evx(17)Gbx(15)Gsx(13)Hox1(21)Hox2(13)Hox3(25)Hox4(24)Hox5(19)Hox6-8(55)
Hox9-13(15)(96)Meox(14)Mnx(15)Pdx(6)       
NKL subclass
Abox(5)Ankx(1)Barhl(16)Bari(4)Barx(10)Bsx(10)Dbx(15)Dlx(35)Emx(22)En(19)
Hhex(10)Hlx(9)Hx(1)Lbx(14)Lcx(1)Msx(22)Msxlx(3)Nanog(15)Nedx(5)Nk1(17)
Nk2.1(18)Nk2.2(15)Nk3(14)Nk4(19)Nk5/Hmx(25)Nk6(19)Nk7(4)Noto(10)Ro(5)Tlx(19)
Vax(12)Ventx(18)         
 
Loci in Nk1 of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
nkx1.2laNK1 transcription factor related 2-like,aNk1Zebrafish 
nkx1.2lbNK1 transcription factor related 2-like,bNk1Zebrafish 
ceh-1C. Elegans Homeobox 1Nk1Nematode 
Nkx1-1 Nk1Mouse 
Nkx1-2 Nk1Mouse 
NKX1-1NK1 homeobox 1Nk1Human 
NKX1-2NK1 homeobox 2Nk1Human 
SlouSlouchNk1Honeybee 
slouslouchNk1Fruitfly 
nkx1-2NK1 homeobox 2Nk1Frog 
nkx1-2laNK1 transcription factor related 2-like aNk1Frog 
nkx1-2lbNK1 transcription factor related 2-like bNk1Frog 
NKX1-1NK1 homeobox 1Nk1Chicken 
NKX1-2 Nk1Chicken 
SlouSlouchNk1Beetle 
Nkx1aNkx1aNk1Amphioxus 
Nkx1bNkx1bNk1Amphioxus