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LIM Class
Families List  Genes List
Isl Family
There are two members of the Isl gene family in humans: ISL1 and ISL2. There is one amphioxus orthologue and one Drosophila orthologue (tailup, tup). The Isl family is part of the LIM homeodomain class. Functions and evolution are reviewed by Hobert and Westphal (2000); human and Drosophila sequence comparisons in Holland et al. (2007).

Reference(s):
Hobert O, Westphal H (2000) Trends Genet 16:75-83.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class LIM :
Isl(14)Lhx1/5(17)Lhx2/9(19)Lhx3/4(15)Lhx6/8(18)Lmx(21)    
 
Loci in Isl of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
isl1islet1IslZebrafish 
isl1lislet1, likeIslZebrafish 
isl2aislet2aIslZebrafish 
isl2bislet2bIslZebrafish 
lim-7LIM domain family 7IslNematode 
Isl1 IslMousemmu-mir-17
Isl2 IslMouse 
ISL1ISL LIM homeobox 1IslHuman 
ISL2ISL LIM homeobox 2IslHuman 
TupTailupIslHoneybee 
isl2ISL LIM homeobox 2IslFrog 
ISL1ISL LIM homeobox 1IslChicken 
TupTailupIslBeetle 
IslIslIslAmphioxus