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PRD Class
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Hopx Family
The Hopx gene family contains a single gene in human (HOPX, formerly called HOP) coding for a protein with an extremely divergent 61 amino acid homeodomain sequence that is not thought to bind DNA (Chen et al. 2002, Shin et al. 2002). It is difficult to deduce the evolutionary origins and affinities of the Hopx gene family using phylogenetic analysis. Holland et al. (2007) argue for placement in the PRD class. There is one orthologue in amphioxus, but none in Drosophila.

Reference(s):
Chen F et al. (2002) Cell 110:713-723.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Shin CH et al. (2002) Cell110:725-735.
 
Families List of Class PRD :
Alx(2)Arx(1)Dmbx(1)Drgx(1)Gsc(2)Hesx(1)Hopx(1)Isx(1)Mix(2)
Nobox(1)Otp(1)Pax3/7(2)Pax4/6(1)Phox(1)Pitx(3)Prrx(2)Rax(1)Sebox(1)
Shox(1)Uncx(1)Vsx(2)       
 
Loci in Hopx of Chicken back to top..
Symbol/LocusNameFamilyOrganismRegulator
HOPXHOP homeoboxHopxChicken