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PRD Class
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Shox Family
There are two human genes in the Shox gene family: SHOX and SHOX2. The SHOX (short stature homeobox) gene is located in the PAR1 pseudoautosomal region of the X and Y chromosomes; haploinsufficiency of SHOX is implicated in the short stature phenotype of Turner syndrome patients who lack one copy of the X chromosome (Rao et al. 1997). Shox has been lost from mouse, although Shox2 is present (Zhong and Holland 2011). There is one amphioxus orthologue and one Drosophila orthologue (CG34367).

Rao E et al. (1997) Nat Genet 16:54-63.
Zhong YF, Holland PWH (2011) BMC Evol Biol 11: 169-204.
Families List of Class PRD :
Loci in Shox of Honeybee back to top..