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PRD Class
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Shox Family
There are two human genes in the Shox gene family: SHOX and SHOX2. The SHOX (short stature homeobox) gene is located in the PAR1 pseudoautosomal region of the X and Y chromosomes; haploinsufficiency of SHOX is implicated in the short stature phenotype of Turner syndrome patients who lack one copy of the X chromosome (Rao et al. 1997). Shox has been lost from mouse, although Shox2 is present (Zhong and Holland 2011). There is one amphioxus orthologue and one Drosophila orthologue (CG34367).

Reference(s):
Rao E et al. (1997) Nat Genet 16:54-63.
Zhong YF, Holland PWH (2011) BMC Evol Biol 11: 169-204.
 
Families List of Class PRD :
Alx(3)Argfx(3)Arx(1)Dmbx(1)Dprx(8)Drgx(1)Dux(36)Esx(1)Gsc(2)
Hesx(1)Hopx(1)Isx(1)Leutx(1)Mix(1)Nobox(1)Otp(1)Otx(4)Pax2/5/8(3)
Pax3/7(2)Pax4/6(2)Phox(2)Pitx(3)Prop(1)Prrx(2)Rax(2)Rhox(3)Sebox(1)
Shox(2)Tprx(5)Uncx(1)Vsx(2)      
 
Loci in Shox of Human back to top..
Symbol/LocusNameFamilyOrganismRegulator
SHOXshort stature homeoboxShoxHuman 
SHOX2short stature homeobox 2ShoxHuman