Home | Human | Mouse | Chicken | Frog | Zebrafish | Amphioxus | Fruitfly | Beetle | Honeybee | Nematode
Total | HomeoReg | Summary | Download | Compare | BLAST | Search (gene symbol, e.g. HOX)

PRD Class
Families List  Genes List
Shox Family
There are two human genes in the Shox gene family: SHOX and SHOX2. The SHOX (short stature homeobox) gene is located in the PAR1 pseudoautosomal region of the X and Y chromosomes; haploinsufficiency of SHOX is implicated in the short stature phenotype of Turner syndrome patients who lack one copy of the X chromosome (Rao et al. 1997). Shox has been lost from mouse, although Shox2 is present (Zhong and Holland 2011). There is one amphioxus orthologue and one Drosophila orthologue (CG34367).

Reference(s):
Rao E et al. (1997) Nat Genet 16:54-63.
Zhong YF, Holland PWH (2011) BMC Evol Biol 11: 169-204.
 
Families List of Class PRD :
Alx(3)Arx(1)Dmbx(1)Drgx(1)Dux(6)Esx(1)Gsc(2)Hesx(1)Hopx(1)
Isx(1)Mix(1)Nobox(1)Obox(36)Otp(1)Otx(3)Pax2/5/8(3)Pax3/7(2)Pax4/6(2)
Phox(2)Pitx(3)Prop(1)Prrx(2)Rax(1)Rhox(36)Sebox(1)Shox(1)Uncx(1)
Vsx(2)         
 
Loci in Shox of Mouse back to top..
Symbol/LocusNameFamilyOrganismRegulator
Shox2 ShoxMouse