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TALE Class
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Tgif Family
The Tgif gene family (within the TALE class) is equivalent to the TGIF gene class of Bürglin and Mukherjee (2007). The Tgif gene family includes two human genes on autosomes and one gene with homologues on the X and Y chromosomes (TGIF2LX and TGIF2LY). The autosomal genes have generated a total of five pseudogenes although some of these are short and represent partial integrants of reverse transcribed mRNA (Holland et al. 2007). Two of the pseudogenes, TGIF2P2 and TGIF2P3 are very similar neighbouring loci that must have originated by tandem duplication after a single integration event. The sex-linked gene may also have arisen by retrotransposition (Blanco-Arias et al. 2002). There is one orthologue in amphioxus, and two tandemly arranged orthologues in Drosophila (achintya, achi and vismay, vis).

Reference(s):
Blanco-Arias P, Sargent CA, Affara NA (2002) Mamm Genome 13:463-468.
Bürglin TR, Mukherjee K (2007) J Mol Evol 65:137-153.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class TALE :
Irx(2)Meis(1)Mkx(1)Pbx(1)Pknox(1)Tgif(2)    
 
Loci in Tgif of Beetle back to top..
Symbol/LocusNameFamilyOrganismRegulator
Tgif1Tgif1TgifBeetle 
Tgif2Tgif2TgifBeetle