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CERS Class
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The CERS (or LASS) homeobox gene class is highly unusual and encodes proteins that seem to be transmembrane in nature (Mizutani and Kihara 2005; Pewzner-Jung et al. 2006). The function of the homeodomain in these proteins is unknown. There are six CERS (ceramide synthase) genes in the human genome, but only five of these include a homeobox sequence and are therefore included in the CERS homeobox gene class (Holland et al. 2007). Amphioxus has a single CERS homeobox gene.

Reference(s):
Mizutani Y, Kihara A, Igarashi Y (2005) Biochem J 2005, 390:263-271.
Pewzner-Jung Y, Ben-Dor S, Futerman AH (2006) J Biol Chem 281:25001-25005.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class CERS :
Cers(6)         
 
Loci in CERS of Chicken back to top..
Symbol/LocusNameFamilyOrganismRegulator
Cers-lCers likeCersChicken 
LASS2LAG1 homolog, ceramide synthase 2CersChicken 
LASS3LAG1 homolog, ceramide synthase 3CersChicken 
LASS4LAG1 homolog, ceramide synthase 4CersChicken 
LASS6LAG1 homolog, ceramide synthase 6CersChicken 
LOC415513similar to LASS3 proteinCersChicken