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LIM Class
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The LIM homeobox gene class includes proteins with LIM domains (zinc-finger-containing protein-protein interaction domains) and a homeodomain. There are other genes that encode LIM domains but not homeodomains; these are not included. The term LIM is derived from the nematode lin-11, mammalian Isl1 and nematode mec-3 genes. There are 12 LIM class homeobox genes in the human genome, in six gene families, and no pseudogenes. There are 7 LIM class homeobox genes in amphioxus (Takatori et al. 2008)

Reference(s):
Hobert O, Westphal H (2000) Trends in Genetics 16:75-83.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Takatori N et al (2008) Dev Genes Evol 218: 579-590.
 
Families List of Class LIM :
Isl(1)Lhx1/5(2)Lhx2/9(2)Lhx3/4(2)Lhx6/8(2)Lmx(3)    
 
Loci in LIM of Frog back to top..
Symbol/LocusNameFamilyOrganismRegulator
isl2ISL LIM homeobox 2IslFrog 
lhx1LIM homeobox 1 Lhx1/5Frog 
lhx2LIM homeobox 2Lhx2/9Frog 
lhx3LIM homeobox 3 Lhx3/4Frog 
lhx4LIM homeobox 4 Lhx3/4Frog 
lhx5LIM homeobox 5 Lhx1/5Frog 
lhx6LIM homeobox 6 Lhx6/8Frog 
lhx8LIM homeobox 8Lhx6/8Frog 
lhx9LIM homeobox 9 Lhx2/9Frog 
lmx1aLIM homeobox transcription factor 1a LmxFrog 
lmx1bLIM homeobox transcription factor 1b LmxFrog 
lmx1cLIM homeobox transcription factor 1cLmxFrog