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POU Class
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Proteins encoded by POU class homeobox genes have a ~75 amino acid POU-specific domain (named from the mammalian genes Pit1 (now Pou1f1), OCT1 and OCT2 (now POU2F1 and POU2F2), and nematode unc-86) N-terminal to a 60-amino acid homeodomain. Together the two domains are known as the bipartite POU domain. There are 15 genes with this structure in the human genome, plus a 16th gene (HDX) that possesses a homeodomain related to POU-type homeodomains but lacking a POU-specific domain. Including the divergent HDX gene, this gene class has 16 human genes in seven gene families; there are also eight pseudogenes (Ryan and Rosenfeld 1997, Holland et al. 2007). Amphioxus has seven genes in six families (Takatori et al. 2008).

Reference(s):
Ryan AK, Rosenfeld MG (1997) Genes Dev 1997, 11:1207-1225.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Takatori N et al (2008) Dev Genes Evol 218: 579-590.
 
Families List of Class POU :
Pou2(1)Pou3(1)Pou4(1)Pou6(1)      
 
Loci in POU of Honeybee back to top..
Symbol/LocusNameFamilyOrganismRegulator
Acj6Abnormal chemosensory jump 6Pou4Honeybee 
NubNubbinPou2Honeybee 
Pdm3Pou domain motif 3Pou6Honeybee 
VvlVentral veins lackingPou3Honeybee