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POU Class
Families List  Genes List
Proteins encoded by POU class homeobox genes have a ~75 amino acid POU-specific domain (named from the mammalian genes Pit1 (now Pou1f1), OCT1 and OCT2 (now POU2F1 and POU2F2), and nematode unc-86) N-terminal to a 60-amino acid homeodomain. Together the two domains are known as the bipartite POU domain. There are 15 genes with this structure in the human genome, plus a 16th gene (HDX) that possesses a homeodomain related to POU-type homeodomains but lacking a POU-specific domain. Including the divergent HDX gene, this gene class has 16 human genes in seven gene families; there are also eight pseudogenes (Ryan and Rosenfeld 1997, Holland et al. 2007). Amphioxus has seven genes in six families (Takatori et al. 2008).

Ryan AK, Rosenfeld MG (1997) Genes Dev 1997, 11:1207-1225.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Takatori N et al (2008) Dev Genes Evol 218: 579-590.
Families List of Class POU :
Loci in POU of Human back to top..
HDXhighly divergent homeoboxHdxHuman 
POU1F1POU class 1 homeobox 1Pou1Human 
POU2F1POU class 2 homeobox 1Pou2Human 
POU2F2POU class 2 homeobox 2Pou2Human 
POU2F3POU class 2 homeobox 3Pou2Human 
POU3F1POU class 3 homeobox 1Pou3Human 
POU3F2POU class 3 homeobox 2Pou3Human 
POU3F3POU class 3 homeobox 3Pou3Human 
POU3F4POU class 3 homeobox 4Pou3Human 
POU4F1POU class 4 homeobox 1Pou4Human 
POU4F2POU class 4 homeobox 2Pou4Human 
POU4F3POU class 4 homeobox 3Pou4Human 
POU5F1POU class 5 homeobox 1Pou5Human 
POU5F1P1POU class 5 homeobox 1 pseudogene 1Pou5Human 
POU5F1P2POU class 5 homeobox 1 pseudogene 2Pou5Human 
POU5F1P3POU class 5 homeobox 1 pseudogene 3Pou5Human 
POU5F1P4POU class 5 homeobox 1 pseudogene 4Pou5Human 
POU5F1P5POU class 5 homeobox 1 pseudogene 5Pou5Human 
POU5F1P6POU class 5 homeobox 1 pseudogene 6Pou5Human 
POU5F1P7POU class 5 homeobox 1 pseudogene 7Pou5Human 
POU5F1P8POU class 5 homeobox 1 pseudogene 8Pou5Human 
POU5F2POU class 5 homeobox 2Pou5Human 
POU6F1POU class 6 homeobox 1Pou6Human 
POU6F2POU class 6 homeobox 2Pou6Human