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ZF Class
Families List  Genes List
Genes in the ZF (zinc finger) class encode proteins with zinc finger motifs in addition to one or more homeodomains. There are 14 members of the ZF homeobox gene class in the human genome (plus one pseudogene), which can be divided into five distinct gene families. There are many additional zinc finger-containing genes in the human genome that do not contain homeobox sequences; these are not included in the ZF homeobox gene class. As argued by Holland et al. (2007), it is logical to include the HOMEZ gene in the ZF class, even though it does not encode zinc fingers, because its homeodomain sequences are clearly related to those encoded by some of the ZF genes. Amphioxus has five ZF-class genes.

Reference(s):
Bayarsaihan D et al. (2003) , Proc Natl Acad Sci USA 100:10358-10363.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class ZF :
Adnp(9)Azfh(1)Tshz(16)Zeb(14)Zfhx(21)Zhx/Homez(22)    
 
Loci in ZF of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
Adnp AdnpZebrafish 
adnpactivity-dependent neuroprotector homeoboxAdnpZebrafish 
homezhomeodomain leucine zipper geneZhx/HomezZebrafish 
LOC556453zinc-finger homeodomain protein 4-likeZfhxZebrafish 
LOC558522similar to zinc finger protein 537TshzZebrafish 
si:ch73-386h18.1si:ch73-386h18.1ZfhxZebrafish 
tshz1teashirt family zinc finger 1TshzZebrafish 
tshz2teashirt zinc finger homeobox 2TshzZebrafish 
tshz3bteashirt zinc finger homeobox 3bTshzZebrafish 
wu:fa03a11wu:fa03a11ZfhxZebrafish 
zeb1zinc finger E-box binding homeobox 1ZebZebrafish 
zeb2bzinc finger E-box binding homeobox 2bZebZebrafish 
Zfhx3-lzinc finger homeobox 3-likeZfhxZebrafish 
Zhl-lZhl/Homeoz likeZhx/HomezZebrafish 
Zhx-lZhx/Homeoz likeZhx/HomezZebrafish 
zhx2zinc-fingers and homeoboxes 2Zhx/HomezZebrafish 
zhx3zinc fingers and homeoboxes 3Zhx/HomezZebrafish 
zag-1Zinc finger plus homeodomain, Axon Guidance 1ZebNematode 
ZC123.3 ZfhxNematode 
Adnp AdnpMouse 
Adnp2 AdnpMouse 
Homez Zhx/HomezMouse 
Tshz1 TshzMouse 
Tshz2 TshzMouse 
Tshz3 TshzMouse 
Zeb1 ZebMouse 
Zeb2 ZebMouse 
Zfhx2 ZfhxMouse 
Zfhx3 ZfhxMouse 
Zfhx4 ZfhxMouse 
Zhx1 Zhx/HomezMouse 
Zhx2 Zhx/HomezMouse 
Zhx3 Zhx/HomezMouse 
ADNPactivity-dependent neuroprotector homeoboxAdnpHuman 
ADNP2ADNP homeobox 2AdnpHuman 
HOMEZhomeobox and leucine zipper encodingZhx/HomezHuman 
TSHZ1teashirt zinc finger homeobox 1TshzHuman 
TSHZ2teashirt zinc finger homeobox 2TshzHuman 
TSHZ3teashirt zinc finger homeobox 3TshzHuman 
ZEB1zinc finger E-box binding homeobox 1ZebHumanhsa-mir-200a; hsa-mir-200b; hsa-mir-205
ZEB2zinc finger E-box binding homeobox 2ZebHumanhsa-mir-138; hsa-mir-200a; hsa-mir-200b; hsa-mir-205; hsa-mir-221
ZEB2P1zinc finger E-box binding homeobox 2 pseudogene 1ZebHuman 
ZFHX2zinc finger homeobox 2ZfhxHuman 
ZFHX3zinc finger homeobox 3ZfhxHuman 
ZFHX4zinc finger homeobox 4ZfhxHuman 
ZHX1zinc fingers and homeoboxes 1Zhx/HomezHuman 
ZHX2zinc fingers and homeoboxes 2Zhx/HomezHuman 
ZHX3zinc fingers and homeoboxes 2Zhx/HomezHuman 
Zfh2Zn finger homeodomain 2ZfhxHoneybee 
zfh1Zn finger homeodomain 1ZfhxFruitfly 
zfh2Zn finger homeodomain 2ZfhxFruitfly 
adnpactivity-dependent neuroprotector homeoboxAdnpFrog 
adnp2ADNP homeobox 2AdnpFrog 
homezhomeobox and leucine zipper encoding Zhx/HomezFrog 
tshz2teashirt zinc finger homeobox 2TshzFrog 
tshz3teashirt zinc finger homeobox 3 TshzFrog 
zeb1zinc finger E-box binding homeobox 1 ZebFrog 
zeb2zinc finger E-box binding homeobox 2 ZebFrog 
zfhx2zinc finger homeobox 2ZfhxFrog 
zfhx3zinc finger homeobox 3ZfhxFrog 
zfhx4zinc finger homeobox 4 ZfhxFrog 
zhx1zinc fingers and homeoboxes 1 Zhx/HomezFrog 
zhx2zinc fingers and homeoboxes 2Zhx/HomezFrog 
zhx2b Zhx/HomezFrog 
zhx3zinc fingers and homeoboxes 3Zhx/HomezFrog 
ADNPactivity-dependent neuroprotector homeoboxAdnpChicken 
TSHZ1teashirt family zinc finger 1TshzChicken 
TSHZ2teashirt family zinc finger 2TshzChicken 
TSHZ3teashirt family zinc finger 3TshzChicken 
ZEB1zinc finger E-box binding homeobox 1ZebChicken 
ZEB2zinc finger E-box binding homeobox 2ZebChicken 
ZFHX3zinc finger homeobox 3ZfhxChicken 
ZFHX4zinc finger homeodomain 4ZfhxChicken 
ZHX1zinc fingers and homeoboxes 1Zhx/HomezChicken 
ZHX2zinc fingers and homeoboxes 2Zhx/HomezChicken 
ZHX3zinc fingers and homeoboxes 3Zhx/HomezChicken 
Zfh1Zinc finger homeodomain 1ZebBeetle 
Zfh2Zinc finger homeodomain 2ZfhxBeetle 
AzfhAzfhAzfhAmphioxus 
TshzTshzTshzAmphioxus 
ZebZebZebAmphioxus 
ZfhxZfhxZfhxAmphioxus 
ZhxZhxZhx/HomezAmphioxus