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ZF Class
Families List  Genes List
Genes in the ZF (zinc finger) class encode proteins with zinc finger motifs in addition to one or more homeodomains. There are 14 members of the ZF homeobox gene class in the human genome (plus one pseudogene), which can be divided into five distinct gene families. There are many additional zinc finger-containing genes in the human genome that do not contain homeobox sequences; these are not included in the ZF homeobox gene class. As argued by Holland et al. (2007), it is logical to include the HOMEZ gene in the ZF class, even though it does not encode zinc fingers, because its homeodomain sequences are clearly related to those encoded by some of the ZF genes. Amphioxus has five ZF-class genes.

Reference(s):
Bayarsaihan D et al. (2003) , Proc Natl Acad Sci USA 100:10358-10363.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class ZF :
Adnp(2)Tshz(4)Zeb(2)Zfhx(4)Zhx/Homez(5)     
 
Loci in ZF of Zebrafish back to top..
Symbol/LocusNameFamilyOrganismRegulator
Adnp AdnpZebrafish 
adnpactivity-dependent neuroprotector homeoboxAdnpZebrafish 
homezhomeodomain leucine zipper geneZhx/HomezZebrafish 
LOC556453zinc-finger homeodomain protein 4-likeZfhxZebrafish 
LOC558522similar to zinc finger protein 537TshzZebrafish 
si:ch73-386h18.1si:ch73-386h18.1ZfhxZebrafish 
tshz1teashirt family zinc finger 1TshzZebrafish 
tshz2teashirt zinc finger homeobox 2TshzZebrafish 
tshz3bteashirt zinc finger homeobox 3bTshzZebrafish 
wu:fa03a11wu:fa03a11ZfhxZebrafish 
zeb1zinc finger E-box binding homeobox 1ZebZebrafish 
zeb2bzinc finger E-box binding homeobox 2bZebZebrafish 
Zfhx3-lzinc finger homeobox 3-likeZfhxZebrafish 
Zhl-lZhl/Homeoz likeZhx/HomezZebrafish 
Zhx-lZhx/Homeoz likeZhx/HomezZebrafish 
zhx2zinc-fingers and homeoboxes 2Zhx/HomezZebrafish 
zhx3zinc fingers and homeoboxes 3Zhx/HomezZebrafish